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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A2
All Species:
40.91
Human Site:
S729
Identified Species:
81.82
UniProt:
O94973
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94973
NP_036437.1
939
103960
S729
L
L
Q
I
G
L
K
S
E
F
R
Q
N
L
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116794
953
104990
S743
L
L
Q
I
G
L
K
S
E
F
R
Q
N
L
G
Dog
Lupus familis
XP_533200
1007
111388
S797
L
L
Q
I
G
L
K
S
E
F
R
Q
N
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P17427
938
104082
S728
L
L
Q
I
G
L
K
S
E
F
R
Q
N
L
G
Rat
Rattus norvegicus
P18484
938
104026
S728
L
L
Q
I
G
L
K
S
E
F
R
Q
N
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
S728
L
L
Q
I
G
L
K
S
E
F
R
Q
N
L
G
Frog
Xenopus laevis
NP_001089303
939
104392
S729
L
L
Q
I
G
V
K
S
E
F
R
Q
N
L
G
Zebra Danio
Brachydanio rerio
XP_001922436
930
103267
S720
L
L
Q
I
G
I
K
S
E
Y
R
Q
N
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
S730
M
L
Q
I
G
V
K
S
E
F
R
Q
N
L
G
Honey Bee
Apis mellifera
XP_394621
937
104937
S726
L
I
Q
I
G
V
K
S
E
F
R
Q
N
L
G
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
N714
G
C
K
L
E
T
R
N
N
L
G
R
L
G
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
D788
F
Y
R
I
T
T
P
D
A
Q
Q
P
Y
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.6
89.3
N.A.
97.2
97.2
N.A.
N.A.
95.3
87.6
84.3
N.A.
69.8
71
66.1
N.A.
Protein Similarity:
100
N.A.
94.5
91.3
N.A.
98.6
98.8
N.A.
N.A.
97.7
94.2
91.1
N.A.
81.4
82.2
78.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
86.6
N.A.
86.6
86.6
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
100
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
84
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
75
0
0
0
0
9
% F
% Gly:
9
0
0
0
84
0
0
0
0
0
9
0
0
9
84
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
92
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
84
0
0
0
0
0
0
0
0
% K
% Leu:
75
75
0
9
0
50
0
0
0
9
0
0
9
84
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
9
0
0
0
84
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
84
0
0
0
0
0
0
9
9
84
0
0
0
% Q
% Arg:
0
0
9
0
0
0
9
0
0
0
84
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
17
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
25
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _